Proprietary nanomedicine platform for targeted delivery of cannabinoids to brain tumors including glioblastoma multiforme
Ottawa, Ontario, April 11
th
, 2019 (GLOBE NEWSWIRE) -- Tetra Bio-Pharma Inc. ("Tetra"
or the "Company") (TSX-V: TBP) (OTCQB: TBPMF), today announced that it has
entered into a collaboration agreement with Ovensa Inc. ("Ovensa") to evaluate
TRIOZANTM, a proprietary nanomedicine platform for targeted delivery of cannabinoids
to brain tumor cells.
"Glioblastoma multiforme (GBM) is a common and fatal type of brain cancer and sadly
took the lives of Senator John McCain and singer Gordon Downey. Our collaboration with
Ovensa will evaluate if TRIOZANTM allows a targeted delivery of cannabinoids to the brain
tumor. There is some published evidence demonstrating the activity of cannabinoids on
brain tumors. If successful this could provide an increased efficacy when this treatment
is used as an adjunct to radiotherapy and or chemotherapy. This technology is also being
investigated for the delivery of an antibody to the brain as part of a collaboration between
Ovensa and Takeda Pharmaceutical. Our collaboration with Ovensa is part of our ongoing
cancer research program,” said Dr. Guy Chamberland, CEO and CSO of Tetra BioPharma.
‘’Ovensa’s TRIOZANTM Delivery Platform allows a high engineering flexibility where
personalized nanomedicines are designed according to various parameters such as
pathology, gene and molecular profile, cell targeting, type of payload, route of
administration and multi-combination. The current collaboration is aimed at engineering
a targeted Glioblastoma Dual-Cannabinoid TRIOZANTM-based therapeutic to achieve
synergistic effects with therapeutic tools such as chemotherapy, radiotherapy and
immunotherapy”, said Ovensa's President and CEO, Mr. Stéphane Gagné.
About Glioblastoma Multiforme (Brain Cancer)
Glioblastoma multiforme (GBM) is the most common and most malignant of the glial
tumors with a 5-year survival rate lower than 5%. Its incidence in most European and
North American countries is approximately 2-3 new cases per 100,000 people per year.
The tremendous unmet need in GBM is substantiated by the lack of treatment progress
and improvement in overall survival in this indication over the last several years.
About Ovensa Inc
Ovensa is a preclinical stage company fighting inherent therapeutic resistance in complex
diseases by generating advanced nanotherapeutics using its proprietary TRIOZANTM
Delivery Platform. The company focuses on advancing its lead drug candidates as well
as generating novel nanotherapeutic candidates in collaboration with pharmaceutical
companies for applications in CNS and immuno-oncology. For more information visit:
www.ovensa.com
About Tetra Bio-Pharma:
Tetra Bio-Pharma (TSX-V: TBP) (OTCQB: TBPMF) is a biopharmaceutical leader in
cannabinoid-based drug discovery and development with a Health Canada authorized,
and FDA reviewed, clinical trials aimed at bringing novel prescription drugs and
treatments to patients and their healthcare providers. The Company has several
subsidiaries engaged in the development of an advanced and growing pipeline of Bio
Pharmaceuticals, Natural Health and Veterinary Products containing cannabis and other
medicinal plant-based elements. With patients at the core of what we do, Tetra BioPharma is focused on providing rigorous scientific validation and safety data required for
inclusion into the existing bio pharma industry by regulators, physicians and insurance
companies. For more information visit: www.tetrabiopharma.com
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Forward-looking statements
Some statements in this release may contain forward-looking information. All statements, other than of
historical fact, that address activities, events or developments that the Company believes, expects or
anticipates will or may occur in the future (including, without limitation, statements regarding potential
acquisitions and financings) are forward-looking statements. Forward-looking statements are generally
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uncertainties, many of which are beyond the Company's ability to control or predict, that may cause the
actual results of the Company to differ materially from those discussed in the forward-looking statements.
Factors that could cause actual results or events to differ materially from current expectations include,
among other things, without limitation, the inability of the Company to obtain sufficient financing to
execute the Company's business plan; competition; regulation and anticipated and unanticipated costs
and delays, the success of the Company's research and development strategies, including the success of
CAUMZ and its other drug candidates, the applicability of the discoveries made therein, the successful and
timely completion and uncertainties related to the regulatory process including the applications for Orphan
Drug Designation, the timing of clinical trials, the timing and outcomes of regulatory or intellectual
property decisions and other risks disclosed in the Company's public disclosure record on file with the
relevant securities regulatory authorities. Although the Company has attempted to identify important
factors that could cause actual results or events to differ materially from those described in forwardlooking statements, there may be other factors that cause results or events not to be as anticipated,
estimated or intended. Readers should not place undue reliance on forward-looking statements. The
forward-looking statements included in this news release are made as of the date of this news release and
the Company does not undertake an obligation to publicly update such forward-looking statements to
reflect new information, subsequent events or otherwise unless required by applicable securities
legislation.
Source: Tetra Bio-Pharma Inc; Ovensa